

🍼 Keep your baby’s skin happy and rash-free — because comfort is the new cool!
Desitin Maximum Strength Baby Diaper Rash Cream features a potent 40% zinc oxide formula that creates a protective moisture barrier, delivering up to 12 hours of relief and prevention. Hypoallergenic and free from parabens and phthalates, this dermatologist-tested cream soothes and heals sensitive skin fast, making it the go-to trusted solution for persistent diaper rash and skin irritation.









| ASIN | B0DS68QFZ5 |
| Best Sellers Rank | #9 in Baby ( See Top 100 in Baby ) #1 in Diaper Creams |
| Customer Reviews | 4.8 4.8 out of 5 stars (47,197) |
| Date First Available | November 7, 2025 |
| Is Discontinued By Manufacturer | No |
| Item model number | 3423 |
| Manufacturer | Kenvue |
| Product Dimensions | 1.69 x 2.38 x 6.94 inches; 9.6 ounces |
S**E
The Only Cream That Works for My Baby’s Sensitive Skin
My baby boy has very sensitive skin and used to get diaper rashes so easily. I’m super careful about what I put on him, and Desitin Extra Strength (the one in the purple container) has been a lifesaver. It’s thick, soothing, and really helps prevent rashes before they even start. I use it at every change and haven’t had a bad rash since. I wouldn’t use anything else—this is a must-have for moms who want to keep their little ones rash-free!
E**S
A household essential that heals fast and protects even better
A household essential that heals fast and protects even better Desitin Maximum Strength Diaper Rash Cream has been around for decades for a reason—it simply works. The 40% zinc oxide formula is thick, soothing, and forms an instant protective barrier that seals out moisture and promotes healing. It’s the go-to for stubborn rashes that other creams can’t touch, often clearing irritation within a day or two. The cream’s texture is dense but spreads evenly, staying in place through multiple diaper changes or overnight use. It’s gentle enough for newborns yet strong enough for adults dealing with chafing or skin irritation from incontinence pads, sweat, or friction. Because it’s hypoallergenic and free of parabens, phthalates, and dyes, it rarely causes irritation even on sensitive skin. The 16-ounce tub is great value—it lasts for months and is far more economical than small tubes. The only minor drawback is that the paste can be hard to remove completely from skin or fabric if overapplied, and it has a mild medicinal scent that not everyone loves. Bottom line: a trusted, dermatologist-tested classic that lives up to its reputation. If you need fast, reliable relief for diaper rash, chafing, or general skin irritation, Desitin Maximum Strength remains the gold standard for both babies and adults alike.
A**C
Excellent Protection for Baby’s Skin!
Desitin Maximum Strength Diaper Rash Cream is a lifesaver for my baby’s sensitive skin. It works fast — I noticed a big improvement after just one or two diaper changes. The thick formula creates a strong barrier that protects against moisture and irritation, and it stays in place really well. A little goes a long way, so the tube lasts quite a while. The smell is mild and pleasant, and it gives me peace of mind knowing my baby is comfortable and rash-free. Definitely a must-have for every diaper bag!
C**S
Only one that works!
Have tried multiple brands and this is the only thing that cures and prevents my baby’s diaper rash!
S**.
Simply excellent
-Desitin Maximum Strength Paste is a staple for our baby’s sensitive skin. The 40% zinc oxide formula provides an excellent protective barrier that isn’t too thick. In our experience, it makes rashes disappear in 1-2 uses. It is extremely reliable and we don’t leave the house without it. We prefer this concentration to the 13% zinc oxide (blue label). We don’t leave the house without it and the 16oz tub provides excellent value.
J**O
Great Product!!!
Great Product! I’m Glad I Found It In A Big Size!!!
S**N
Good product
This jar lasted just about a year. Great for prevention but also helps with healing. Not too easy to get off your hands
G**E
Great price
Great price!
A**A
Atenção e presteza no atendimento
R**H
وصلني المنتج مكسور ومتسرب ومغطى مكان الكسر بلاصق شفاف ، اي انه يعلم بالكسر وقام ببيعه
M**5
Expired
Z**I
ممتاز استخدمه ك وقاية يمنع حدوث تسلخات الحفاظ
S**S
Llegó muy bien, siempre les funciona muy bien esta pomada a mis bebés.
Trustpilot
3 weeks ago
1 month ago