L-Methylfolate 10 mg - Supports a Healthy Mindset - Active Folate for Methylation Support & Biochemical Reactions - Highly Bioavailable - 90 Servings - 90 Capsules

These are a perfect size. 10mg works best for me. Tried higher amount and a lesser amounts, not right for me. So staying with this 10mg and this company's products.

I take L-Methylfolate for Folate Anemia / Folic Acid Anemia. This is the generic version of prescription Deplin with no doctor visit or prescription needed. I take this product: breakfast, lunch, dinner and in the evening before bed. My Anemia is severe. With this product I get relief. I prefer it over Deplin for the smaller dose per pill, smaller pill size and lower cost. The pills are a gel cap so they dissolve quickly and easily in the stomach. The pills are a size 3 so they are very small. For more details on what this product does and how it works please see Deplin.com for the prescription version and the Mayo Clinic website for details on Folate/Folic Acid Anemia. Due to my Iron Anemia and my Folate Anemia I feel cold all the time, exhausted, my mood is unstable where I am prone to Major Depression. I am unresponsive to Anti-depressants since my problem is of a medical nature and not a chemical imbalance like a psychiatrist would treat. I tried psychiatry and it did not help. Once I was put on L-Methylfolate I got better. My energy came up. I was no longer exhausted. My mood improved and I was no longer suicidal or depressed. I got my life back. It has changed my life. My doctor added GABA to my regimen as he said, "If L-Methylfolate works you also need GABA." The combo of GABA, Amino Acid Complex and L-Methylfolate has brought me back to "normal" and everything is smooth sailing now. Supplements can and do change lives. If you have a genetic problem, digestive problem or some other problem that causes your body to not hang onto your vitamins, minerals, Electrolytes or Amino Acids it is important to take supplements as food alone will not work. My digestive problems so I can not hold onto my vitamins, minerals and Amino Acids or Electrolytes runs in my family and doctors suspect is a genetic problem.

I have a homozygous MTHFR mutation and also have to take metformin, which lowers folate. Since I am allergic to the dyes added to Deplin, I needed a dye-free substitute. This really helped me with irritability and extremely treatment-resistant depression. Within a few days of taking this I no longer felt the need to lash out at people around me. I also appreciate that the company uses so few added ingredients. I don't have the anxiety I usually get from high-dose B-vitamins (I have PTSD and am more sensitive to supplements with that side effect). After a few months of taking this, I feel more prone to nausea/dizziness (low-blood pressure is an issue with high-dose B vitamins, from what I am aware) so you may need to back off the dose after awhile. Just a heads up; if you think you may also have MTHFR - there is now a genetic test. It's very new so many doctors don't know about it.

I've used this particular brand and formulation methylfolate for more than 6 months--one 10 mg capsule a day is fine for me. The price is excellent for this size dose. If you need to supplement with methylfolate, you likely need 2 mg a day or higher. (However, I am not a physician and do not presume to know what is best for anyone else, especially since each person may have different needs.) I wouldn't bother with the more common 800 mcg (.8 mg caps or tablets) available from most other manufacturers. They are usually around the same price for a much smaller amount of nutrient. The manufacturer calls this product "pharmaceutical grade." I don't know whether it matters that this is the calcium-salt formulation vs. the glucosamine-salt variation used in Quatrefolic. I've read that some people's digestive systems may tolerate one better than the other. There's a very slight difference in the total percentage of pure methylfolate molecule in the two formulations. I've used both types for over a year. This product and several other brands are worthy alternatives to prescription Deplin. There's no need to get a prescription to get a good methylfolate supplement. These products are known to assist in the efficacy of antidepressant medications and with other ailments, particularly in people with MTHFR genetic defect (40% of the population, by some estimates). Research methylfolate online; there are many resources available. Metabolic Maintenance has a good video on this product on YouTube.

Okay; Metabolic Maintenance ONLY makes MTHF with the preferred form; L-5-Methyltetrafolate! Anyone who complains about the label has only read the front and failed to look at the actual ingredients. They can name it 'Buttercup extract' or 'Unicorn Poop' if they want but what matters is the ingredients folks. This is a lovely product containing L-5-MTHF and Calcium Salts. That's it. No switcheroo going on. It is exactly what your doctor/neurologist/naturopath is telling you to get. Don't believe me; go to their website for Pete's sake! Take the bottle to your doc and have him/her approve/disapprove it. Do a bit of research to find out which forms are legit and which aren't and you will see that some people pay zero attention to the world around them yet believe themselves to be experts with their "Google Doctorates of Pharmacology"! ACK! I am enjoying this product. It may have a bit TOO much of an oompf for me when it gets all absorbed and the serotonin gets to working overtime. I'm a bit sleepy and lack any appetite. Not that the appetite thing is a bad thing! :D Anywho. Great product. Minimal filler for dispersion and absorption. Excellent results; carefully weaning off Citalopram and bupropion with the aid of my therapist and GP and feeling human again. Not that I've known what that is for several decades. Ugh. I'm actually spunky enough to call people on the carpet when they mislead people! teeheehee.