Nature MadeSAM-e Complete 400 mg, Dietary Supplement for Mood Support, 36 Tablets, 36 Day Supply

May be a placebo but it’s working for me. Takes irritably down a notch and makes my energy level higher. I take them usually first thing in the morning with a glass of water.

Good product

For context I struggle with bouts of depression and low moods which affect my productivity levels, resulting in making my depression worse. I’ve been on antidepressants for years, and they work fine until they don’t. If you know, you know.With that being said, I got pretty tired of the whole having to start a new medication and waiting 6 weeks + just to see if it works for me, every time my medication stops working. It’s a tedious process to go through every so often. I have a friend with seasonal depression that told me to try these.To be honest I had zero expectation of this helping at all because my thought process was that this is not a real medication, it’s just the way I’ve been conditioned to think because of so many years of me being on ssri’s, etc.I am here to tell you they really do work. I don’t know what’s in these supplements or the science behind it, all I know is that this has truly been heaven sent for me. I started taking these and around day 3 was when I had the realization that I hadn’t felt sad and I was generally in a good mood.I’m not saying I was super cheerful and upbeat, but my mood felt good, I didn’t feel down, I was getting things done and it’s just a feeling of normalcy.I’ve been taking them since 2021 now, on and off. I got off of my antidepressants since (of course under my doctors supervision) I can’t say enough good things about these supplements. I don’t take them every single day. The way I use them is that once that little twinge of feeling down/sad/low hits me, I immediately start taking them. They work quickly, at least for me. I know some people say they have to take them for a certain amount of time before they start working, but that’s not my experience.In my experience they work almost immediately (compared to SSRI’s) by the second or third day is usually how long it takes for me. I’ll take them for about 2 weeks then stop. I think that’s the key, because your body doesn’t get used to it as opposed to taking something every day.And that’s really it. If I feel a bout coming on, I take them, then stop. Another thing I’ve noticed is that the bouts of depression don’t come on no where near as often as they used to. If your story is similar to mine, I highly recommend these. They will literally change your life.

Great buy at works but I am taking two 400 mg tabs daily.Is up to you what works for you

Seems to work well

This stuff works wonders!I went through a pretty rough patch in my life. I lost 2 dogs, 1 cat, and my best friend/roommate to cancer all within 2 years.My doctor placed me on Welbutrin but that stuff made me completely insane! 1 day I was angry, 1 day I was completely miserable, 1 day I was unbearably tired. I also had a horrible headache when I was taking it. I felt like was a mindless zombie on Welbutrin. I decided to stop taking the Welbutrin before it settled into my system.I figured I would try and go the more natural route after reading all the side effects of the other anti-depressant medications they have available. I first tried Kira St Johns Wort Tablets - 45 Tablets. These seemed to help, but it was very mild and not consistent in keeping my mood up.Then...there was Nature Made Sam-E. I tried some of the store brand Sam-E's to try and keep costs down, however, none of the other brands even came close to working as good as Nature's Made. And if you shop around you can usually find a buy one get one free at Walgreens, Giant, CVS, or even Amazon!This stuff helped me through the roughest time of my life. I've been using Sam-e well over 2 years now and if I even missed one dose I would immediately notice a huge change in my mood. I have been taking 1 400mg pill a day since I started. Once in a while I would take took 2 or 3 in a day.I just started taking 1 pill every other day to give my body a break because I do not like to be dependent on any type of medication. But for those super hard times, this stuff really helped to get me through.I highly recommend trying Sam-E. Especially before trying any prescription anti-depressants. It is a natural approach to overcoming depression, has low to no side effects at all (I never experienced any), and even if it does not help with improving your mental health, at least it is supporting your joints. ;)Hope this helps!