• SAM-e Supplements: SAMe is involved in methylation reactions and in the synthesis of phosphatidylcholine, a substantial constituent of grey matter within the brain and cellular membranes*.
• Biologically Active Form SAMe Supplement: SAMe formula provides 400 mg from 800 mg of SAMe tosylate disule and is enteric-coated to ensure a biologically active product*.
• SAMe Supplement: SAMe supports the production of y connective tissue;* SAMe sm supports glutathione synthesis for antioxidant and liver support*.
• y-Friendly SAM-e Supplements: These s are vegan, wheat free, gluten free, soy free, dairy free, egg free, fish/shellfish free, peanut/tree nut free, and sesame free.
• Suggested Use for SAMe supplement: Adults take 1 a day on an empty stomach or as directed by your qualified care professional.

Product Description ------------------- Jarrow Formulas SAMe provides SAM-e (S-Adenosyl Methionine), a naturally derived compound that plays a role in supporting various bio systems in the body.* Each of Jarrow Formulas SAM-e provides 400 mg of SAM-e to provide benefits. Jarrow Formulas SAM-e offers a wide array of benefits that can support various aspects of your and well-being.* SAM-e supports joint , and liver function.* Jarrow Formulas SAM-e is non-GMO, vegan-friendly, and gluten free, making it an ideal choice for those with dietary restrictions.* These s are also wheat free, soy free, dairy free, egg free, fish/shellfish free, peanut/nut free, and sesame free.* Taking Jarrow Formulas SAM-e is simple and convenient. Adults should take 1 per day on an empty stomach or as directed by your qualified care professional.* At Jarrow Formulas, we aren't your typical company. We believe everyone has the right to feel good in their own body. Jarrow Formulas’ original goal has always remained the same: To design superior dietary supplements that help empower individuals to take charge of their own .*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. .com ---- Jarrow Formulas SAM-e 400, 400mg, 30 s -------------------------------------------- At a Glance: ------------ * Contributes to the proper functioning of many bio systems * Ideal for those wanting to optimize cognitive function, mood, energy levels, liver activity and joint * * Preserved bioavailability through low-temp and low-moisture manufacturing * Processed without solvents * Protected from degradation via enteric coating and blister-packaging SAM-e contributes to the proper functioning of many bio systems. S-adenosyl-L-methionine (SAM-e) is an amino derivative clinically documented to benefit brain, liver and joint function*. View larger ( https://images-na.ssl-images-.com/images/G/01/hpc/detail-page/c26-B0013OSJU0-2-l.png ) . S-adenosyl-L-methionine (SAM-e) is an amino derivative clinically documented to benefit brain, liver and joint function.* Found in all living cells, SAM-e is called "activated methionine" and is formed via combination of ATP with methionine. Somewhat counterintuitively, however, methionine supplementation does not elevate SAM-e levels in the body. Rather, it elevates problematic cysteine. SAM-e has undergone many clinical trials involving thousands of human subjects. Researchers have identified many structure- and function-based benefits of SAM-e involving over 40 bio processes. It is a bio workhorse with various diverse effects on the body, including improving liver function, supporting joint and lifting mood.* Liver Detoxification -------------------- SAM-e sm supports glutathione (GSH) synthesis and glutathione-dependent enzymes, which support liver function.* GSH, the chief antioxidant and detoxifier inside cells, scavenges free radicals produced during carbohydrate breakdown for energy. Taurine is another end product of SAM-e sm. GSH and taurine are important for liver detoxification.* Brain Function -------------- SAM-e supports brain function by its methylation effects.* Methylation is the transfer of a methyl group (one carbon and three hydrogen atoms, CH3) from one molecule to another. SAM-e is the most important of all methyl-donors in mammalian sm. Donation of methyl groups supports numerous c processes including brain function, energy production and sm. Neurotransmitters, substances involved in nerve cell communication, are also products of methylation. These compounds include L-DOPA, dopamine, serotonin, epinephrine and phosphatidylcholine (in lecithin). SAM-e is thought to benefit cognitive by supporting the production of such critical brain messengers.* In fact, many people report noticeable positive effects on brain and mood after only taking it for a short time.* Energy Production ----------------- Methylation from SAM-e is also critical for creatine production. Creatine tes are important for ADP to ATP recycling and storing energy for immediate needs. Supporting creatine levels may help maximize physical performance, reduce exercise igue and improve recovery after exercise.* Longevity --------- A y young body manufactures all the SAM-e it needs. However, with age, people are less able to produce adequate SAM-e. This may contribute to declining on many levels. Fortunately, these disturbances are often boosted by SAM-e supplementation.* In addition, methylation of is an important part of repair. De-methylation of contributes to the aging process. Proper methylation, via substances such as SAM-e, positively influences longevity.* y Connective Tissue ------------------------- Research has shown that regular SAM-e supplementation helps support joint , and is used regularly in Europe to promote joint mobility and comfort.* Not All SAM-e is Created Equal ------------------------------ SAM-e exists in two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is inactive. Jarrow Formulas SAM-e is predominantly the active form. It is made naturally by microbiological fermentation and then specially processed, without solvents, to preserve 68-80 percent (S,S) SAM-e, the highest active level available. SAM-e is a highly reactive molecule and very fragile. It degrades rapidly under high heat or humidity. Improper handling of SAM-e can cause degradation in a matter of hours. Thus, the manufacturing process for Jarrow Formulas SAM-e is done under low temperature and low humidity, and the is enteric coated and blister-packed. cokinetic studies show that oral supplementation of SAM-e is most effective when enteric-coated by special tric fluid-resistant polymers, resulting in maximum blood levels.* Note: ----- Side effects are rare and appear to be limited to trointestinal disturbances. This product complies with the proposed USP Monograph for SAM-e. Warning: -------- Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using. Individuals with Parkinson's disease, bi-polar disorder or manic depression should not use SAM-e. About Jarrow Formulas --------------------- Jarrow Formulas' complete line of over 350 tional products includes s, minerals, probiotics, standardized al concentrates, amino s, enzymes and enteral tion products. Customers can be assured of purity, value and potency when choosing these products. What's in the Box ----------------- Jarrow Formulas SAM-e 400, 400mg, 30 s. Other Products from Jarrow Formulas: ------------------------------------