ProferrinES- 10.5mg of high Absorbing Heme Iron Polypeptide. Made in The USA. 30 Tablets. Easy on The Gut. Not affected by Coffee, Calcium, or PPI's.

When I went to my annual appointment with my pcp, u was complaining about being really tired all the time. He tested my iron and ferritin levels and lo and behold my ferritin levels were stupid low. I tried other iron supplements but the side effects were pretty bad.A family friend suggested that I try this and I’m so glad she did. I feel like it works better (I’m not as tired) and the side effects aren’t as bad (not as constipated). I’m very impressed and thankful.

I waited a couple months to review. I'll be honest, I've always been skeptical of OTC supplements but after experiencing female pattern hair loss, I decided to give these iron supplements a try. They're gentle on my stomach, I feel my energy improving, and my hair is growing back in conjunction with minoxidil. For women with heavy menstrual cycles and hair loss, I recommend this to your daily routine.

I had trouble taking other iron supplements. This one has had no uncomfortable side effects.

I usually can't take ANYTHING on an empty stomach.. I gave this a run for it's money and took 1 in the morning by itself and I didn't get nauseous or anything which is incredible for an iron supplement nonetheless. Will update my review as I retest my iron. I will be taking 3 separately through the day due to chronic iron deficiency that's gone on for decades.

This iron supplement necessary for me because of anemia. I initially took ferrous sulfate tablets but they caused stomach pains. When I looked in the medical literature, heme-based iron supplements appeared to be the best absorbed by the body and to cause no intestinal distress. And that was true for me. However, they are much more expensive than the ferrous sulfate tablets and, for me, they are uncomfortably large to swallow. I manage but I would rather take two small ones than this one large tablet. They are, as promised, relatively expensive.

I’ve been using Profferin iron supplements for years now, and they’ve made a noticeable difference in my energy levels during runs. As a runner, I love that they help keep my iron levels balanced without upsetting my stomach, allowing me to perform at my best.

23 days of proferrin, and my ferritin has gone from 18 to 32. No side effects to speak of, except that I can run with energy again. It is such a gift to feel my strength again, like youth. I'm continuing with this.I was taking iron bis-glycinate, but while effective when taken on an empty stomach, I felt like I had swallowed a balloon. When I took iron bis-glycinate with meals (away from calcium), it was not effective after 4 months of use.I take proferrin with meat stock first thing in the morning; apparently it absorbs better in the presence of amino acids: "free amino acids as cysteine, lysine and histidine enhanced heme and ionic Fe absorption in experimental models". Also iron absorption is apparently not sensitive to calcium in doses of less than 800 mg at a time. "Calcium does not inhibit the absorption of 5 milligrams of nonheme or heme iron at doses less than 800 milligrams". Where other forms of iron are inhibited by phytates and polyphenols, heme iron is not. Lastly, I understand (hopefully correctly) that heme iron may cause less oxidative stress than other forms. I hope that as a result, it lowers the risk of Alzheimer's disease associated with iron supplementation.Update: I was taking 1 pill per day at the time of this review. Since then my ferritin levels dropped to 20, so I began taking 2 per day. Fortunately I did this without any gastrointestinal upset, but unfortunately, 2/day only brought my ferritin up to 21 (I got this blood test result back today). Iron repletion is obviously extraordinarily complex. I'm baffled by it.Update July 2018:My ferritin dropped to 20, then to 17, 13, and finally to 10 while taking approximately 7 proferrin per week. During that time I tried alternating schedules, taking it with broth, lactoferrin, pepsin. Nothing worked. Once my ferritin had dropped to 10, I decided to take 30 mg per day, which is apparently the max you can take without causing expression of Hepcidin (prevents the uptake of iron). Also, I had been inspecting my stool (I know, gross...) and found pockets of dry black powder from undissolved proferrin pills. These pills look like black charcoal on the inside, which is probably why the coat is colored (green). Obviously absorption won't happen if they haven't dissolved.I started taking 3 pills (30 mgs) each morning, all at once, on an empty stomach, away from calcium. Most importantly, I cut each pill in half before taking, which seemed to help disintegration because I found no more black powder in stools. As a result, my ferritin climbed back up to 17 after 1 month of this routine. I'll continue checking ferritin levels each month until it has reached a steady state. Hopefully no more downturns.Update November 2018:My monthly ferritin levels have continued to rise on the schedule of three pills per day, cut, on an empty stomach, and away from calcium. Here are my ferritin results (ng/ml): August (16), September (21), October (25), and November (40). Awesome. Feeling so much better.